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KMID : 0360220160570010161
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Journal of the Korean Ophthalmological Society
2016 Volume.57 No. 1 p.161 ~ p.166
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Systemic Lupus Erythematosus Presenting as Monocular Elevation Deficiency
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김승우:Kim Seung-Woo
김용현:Kim Yong-Hyun/정승아:Chung Seung-Ah
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Abstract
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Purpose: To report a case of monocular elevation deficiency as the presenting manifestation of systemic lupus erythematosus (SLE).
Case summary: A 23-year-old, otherwise healthy female presented with a 3-day history of vertical diplopia and headache. She had a left hypotropia, which worsened in adduction and supra-duction and a profound inferior oblique underaction (-3). Magnetic resonance imaging showed an enhancement around the left superior oblique muscle and multiple infarctions in the left midbrain. On repetitive serological tests, anemia, lymphopenia, and anti-phospholipid antibody were positive. A presumptive diagnosis was a myositis of left superior oblique muscle and hyper-coagulation related with anti-phospholipid antibody. Two months after high-dose steroid treatment, the vertical diplopia was resolved. Five months later, the left hypotropia recurred as a more severe form with the inability to elevate the left eye in all directions. In addition, the infarction associated with vasculitis recurred in the left midbrain. As the treatment with high-dose steroid failed to relieve her ocular symptoms, recession of the left inferior rectus was performed 8 months later. One month after the surgery, she developed multiple lesions of erythematous nodosa with tenderness. Skin biopsy of the lesion in the fingers showed the histological findings consistent with lupus.
Conclusions: Eye movement abnormality can be an initial manifestation of SLE, which should be considered as a differential diagnosis especially in young female patients.
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KEYWORD
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Anti-phospholipid antibody, Monocular elevation deficiency, Systemic lupus erythematosus
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